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中文人类
TNFSF14 - TNF Superfamily Member 14
Alias:
LTg
CD258
HVEML
LIGHT
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这个基因编码的蛋白质是肿瘤坏死因子(TNF)配体家族的一员。这种蛋白质是TNFRSF14的配体，TNFRSF14是肿瘤坏死因子受体超家族的一员，也被称为疱疹病毒进入介质(HVEM)。这种蛋白质可能作为辅助刺激因子，激活淋巴细胞，并阻止疱疹病毒感染。这种蛋白质已被证明能刺激T细胞的增殖，并触发各种肿瘤细胞的凋亡。这种蛋白质还被报道能阻止肿瘤坏死因子α诱导的原代肝细胞凋亡。已经报道了两个可变剪接的转录本变异体，它们编码不同的异构体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TNFSF14 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
