人类

ADAM19 - ADAM Metallopeptidase Domain 19

Alias:
MLTNB
FKSG34
MADDAM
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码ADAM(整合素和金属蛋白酶结构域)家族的一员。这个家族的成员是结构上与蛇毒整合素有关的膜锚定蛋白,并与涉及细胞间和细胞基质相互作用的各种生物过程有关,包括受精、肌肉发育和神经发生。这个成员是一个I型跨膜蛋白,作为树突状细胞分化的标志。已经证明它是一个活跃的金属蛋白酶,可能参与正常的生理过程,如细胞迁移、细胞粘附、细胞间和细胞基质相互作用以及信号传导。据推测,它在癌症、炎症性疾病、肾脏疾病和阿尔茨海默病等病理过程中发挥作用。[由RefSeq,2013年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
23
98472 bp
105.00
55
--
8
7

ADAM19 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top