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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ADAM19 - ADAM Metallopeptidase Domain 19
Alias:
MLTNB
FKSG34
MADDAM
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码ADAM(整合素和金属蛋白酶结构域)家族的一员。这个家族的成员是结构上与蛇毒整合素有关的膜锚定蛋白,并与涉及细胞间和细胞基质相互作用的各种生物过程有关,包括受精、肌肉发育和神经发生。这个成员是一个I型跨膜蛋白,作为树突状细胞分化的标志。已经证明它是一个活跃的金属蛋白酶,可能参与正常的生理过程,如细胞迁移、细胞粘附、细胞间和细胞基质相互作用以及信号传导。据推测,它在癌症、炎症性疾病、肾脏疾病和阿尔茨海默病等病理过程中发挥作用。[由RefSeq,2013年5月提供]
Related ID:
NCBI:8728
ENSEMBL:ENSG00000135074
HGNC:197
UNIPROT:Q9H013
OMIM:603640
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8728
3
23
98472 bp
105.00
55
--
8
7
ADAM19 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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Transcript
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No data available
* This data comes from NCBI.
Gene Expression
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Name
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References Literature
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