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中文人类
TRADD - TNFRSF1A Associated Via Death Domain
Alias:
Hs.89862
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这个基因编码的蛋白质是一个含有死亡结构域的适配器分子，可以与TNFRSF1A/TNFR1相互作用，并调节程序性细胞死亡信号传导和NF-kappaB激活。这个蛋白质可以与适配器蛋白TRAF2结合，减少TRAF2对凋亡抑制蛋白（IAPs）的招募，从而抑制由TRAF2介导的凋亡。这个蛋白质还可以与受体TNFRSF6/FAS和适配器蛋白FADD/MORT1相互作用，并参与Fas诱导的细胞死亡途径。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TRADD Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
