人类

NCOA1 - Nuclear Receptor Coactivator 1

Alias:
SRC1
KAT13A
RIP160
F-SRC-1
bHLHe42
bHLHe74
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质作为类固醇和核激素受体的转录共激活子。它是p160/类固醇受体共激活子(SRC)家族的一员,与其他家族成员一样,具有组蛋白乙酰转移酶活性,并包含核定位信号、bHLH和PAS结构域。这个基因的产品直接结合核受体,并以激素依赖的方式刺激转录活性。已经识别出编码不同异构体的可变剪接转录变异体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
15
23
279449 bp
156.76
85
--
11
41

NCOA1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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