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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
KLF7 - KLF Transcription Factor 7
Alias:
UKLF
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Kruppel样转录调节因子家族的一员。这个家族的成员可以调节细胞增殖、分化和生存,并在C端含有三个C2H2锌指,可以结合GC丰富位点。这个蛋白质可能通过抑制胰腺β细胞中胰岛素的表达和分泌以及去调节脂肪细胞中脂肪细胞因子的分泌,从而促进2型糖尿病的发展。这个基因的一个假基因位于染色体3的长臂上。可变剪接导致了多个转录变异体。[RefSeq,2012年8月提供]
Related ID:
NCBI:8609
ENSEMBL:ENSG00000118263
HGNC:6350
UNIPROT:O75840
OMIM:604865
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8609
14
4
99715 bp
33.36
23
--
6
10
KLF7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
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Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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