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中文人类
AKR7A2 - Aldo-keto Reductase Family 7 Member A2
Alias:
AFAR
AKR7
AFAR1
AFB1-AR1
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这个基因编码的蛋白质属于醛/酮还原酶(AKR)超家族和AKR7家族，参与醛和酮的解毒。AKR7家族由3个基因组成，这些基因位于1号染色体的p臂上。这种蛋白质被认为位于高尔基体中，催化NADPH依赖的琥珀酸半醛还原为内源性神经调质，γ-羟基丁酸。它也可能作为解毒酶，在还原黄曲霉毒素B1和2-羧基苯甲醛中发挥作用。可变剪接导致多种转录变体。[由RefSeq提供，2016年3月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
AKR7A2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
