人类

PIAS1 - Protein Inhibitor Of Activated STAT 1

Alias:
GBP
ZMIZ3
DDXBP1
GU/RH-II
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码激活的STAT蛋白抑制剂(PIAS)家族的一员。PIAS蛋白作为SUMO E3连接酶发挥作用,并通过调节目标蛋白的泛素化在许多细胞过程中扮演重要角色。这个蛋白作为众多细胞途径的转录协同调节因子扮演核心角色,包括STAT1和核因子kappaB途径。交替剪接导致多个转录变异体。[RefSeq,2016年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7
14
139533 bp
71.84
50
--
5
40

PIAS1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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