人类

LGR5 - Leucine Rich Repeat Containing G Protein-coupled Receptor 5

Alias:
FEX
HG38
GPR49
GPR67
GRP49
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一个富含亮氨酸的重复序列受体(LGR),属于G蛋白偶联、7-跨膜受体(GPCR)超家族成员。这个编码的蛋白质是R-spondin的受体,参与典型Wnt信号通路。这个蛋白质在胚胎后发育过程中在成年肠道干细胞的形成和维护中发挥作用。已经发现这个基因有几个转录变异体,编码不同的异构体。[由RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
18
147182 bp
100.00
41
--
15
16

LGR5 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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