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中文人类
TSLP - Thymic Stromal Lymphopoietin
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这个基因编码一种造血细胞因子，提议通过由胸腺基质淋巴细胞生成素受体和IL-7Rα链组成的异源二聚体受体复合物进行信号传导。它主要影响髓样细胞，并诱导单核细胞释放吸引T细胞的趋化因子，增强CD11c+树突状细胞的成熟。该蛋白质促进与各种炎症性疾病免疫相关的辅助型2（TH2）细胞反应，包括哮喘、过敏炎症和慢性阻塞性肺病。因此，该蛋白质被认为是治疗这些疾病的潜在治疗靶点。此外，该基因的剪接变异导致多种转录变异体。[RefSeq，2020年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TSLP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
