人类

TRIM5 - Tripartite Motif Containing 5

Alias:
RNF88
TRIM5alpha
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是三部分模体(TRIM)家族的一员。TRIM结构包括三个锌结合结构域,一个RING,一个B框1型和B框2型,以及一个螺旋螺旋区域。蛋白质通过螺旋螺旋区域形成同源寡聚体,并定位到细胞质体中。它似乎作为E3泛素连接酶发挥作用,并自身泛素化以调节其亚细胞定位。它可能参与逆转录病毒限制。这个基因有多个可变剪接转录变异体,编码不同的异构体。[由RefSeq,2009年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
12
8
96440 bp
56.34
46
--
10
32

TRIM5 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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