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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PPP1R16A - Protein Phosphatase 1 Regulatory Subunit 16A
Alias:
MYPT3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
肌轻链激酶和磷酸酶(MLCP)复合体控制调节肌轻链的磷酸化状态,这对于肌肉和细胞内移动至关重要。MLCP通常包含一个催化蛋白磷酸酶1(PP1c)亚基,一个肌动蛋白磷酸酶靶向(MYPT)亚基,以及另一个较小的亚基。这个基因编码的蛋白质代表了一个MYPT亚基,负责将PP1c引导到其预期的靶标。然而,尽管其他MYPT成员的磷酸化导致PP1c失活,但编码蛋白质的磷酸化被蛋白激酶A激活。[由RefSeq,2020年1月提供]
Related ID:
NCBI:84988
ENSEMBL:ENSG00000160972
HGNC:14941
UNIPROT:Q96I34
OMIM:609172
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
84988
25
12
24140 bp
57.81
34
--
2
2
PPP1R16A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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CAS Number
Status
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Link
No data available
References Literature
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