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中文人类
ATG4D - Autophagy Related 4D Cysteine Peptidase
Alias:
APG4D
AUTL4
APG4-D
HsAPG4D
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自噬是一种细胞内的内源蛋白质和受损细胞器被破坏的过程。自噬被认为对细胞的稳态和分化、形态发生、非凋亡性死亡和衰老过程中的细胞重塑是必不可少的。一些恶性肿瘤中自噬水平降低，自噬在控制与癌症相关的无调控细胞生长中的作用已被提出。这个基因属于自噬相关蛋白4（Atg4）家族的C54内肽酶。这个家族的成员编码在自噬体生物发生中起作用的蛋白质，自噬体将细胞质和细胞器包裹以通过溶酶体进行降解。可变剪接导致多个转录变异体。[RefSeq,2013年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ATG4D Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
