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中文人类
CDC42BPA - CDC42 Binding Protein Kinase Alpha
Alias:
MRCK
MRCKA
PK428
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这个基因编码的蛋白质是丝氨酸/苏氨酸蛋白激酶家族的成员。这个激酶包含多个功能结构域。其激酶结构域与肌营养不良蛋白激酶(DMPK)高度相似。这个激酶还包含一个Rac互动结合(CRIB)结构域，已经证明它可以结合CDC42。它可能作为CDC42下游效应子发挥作用，调节CDC42诱导的外周肌动蛋白形成，并促进细胞骨架重组。已经描述了多种可变剪接转录变异体。[由RefSeq，2018年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CDC42BPA Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
