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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
OGT - O-linked N-acetylglucosamine (GlcNAc) Transferase
Alias:
OGT1
HRNT1
MRX106
XLID106
HINCUT-1
O-GLCNAC
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个糖基转移酶,催化O-糖苷键中单个N-乙酰葡萄糖胺添加到丝氨酸或苏氨酸残基上。由于磷酸化和糖基化都竞争相似的丝氨酸或苏氨酸残基,这两个过程可能竞争位点,或者它们可以通过空间或静电效应改变附近位点的底物特异性。该蛋白质包含多个四肽重复序列,对于底物的最佳识别是必需的。已经发现这个基因的替代剪接转录变异体编码不同的异构体。[RefSeq,2009年10月提供]
Related ID:
NCBI:8473
ENSEMBL:ENSG00000147162
HGNC:8127
UNIPROT:O15294
OMIM:300255
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8473
2
22
42789 bp
116.92
102
1
4
44
OGT Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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