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中文人类
GPT2 - Glutamic--pyruvic Transaminase 2
Alias:
ALT2
GPT 2
MRT49
NEDSPM
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这个基因编码线粒体的丙氨酸转氨酶，这是一种吡哆醇酶，可以催化丙氨酸和2-氧代谷氨酸之间的可逆转氨作用，生成丙酮酸和谷氨酸。丙氨酸转氨酶在许多组织中，包括骨骼肌、肾脏和肝脏，在糖异生作用和氨基酸代谢中发挥作用。在肝细胞系中，激活转录因子4在代谢应激条件下上调这个基因的表达。这个基因的功能丧失突变与发育性脑病有关。可变剪接导致多个转录变异体。[由RefSeq，2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GPT2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
