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中文人类
PLA2G12B - Phospholipase A2 Group XIIB
Alias:
GXIIB
FKSG71
PLA2G13
GXIIIsPLA2
sPLA2-GXIIB
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这个基因编码的蛋白质属于磷酸脂酶A2（PLA2）酶家族，该家族在甘油脂水解中发挥作用，释放游离脂肪酸和溶血磷脂。这个家族成员具有改变的磷脂结合特性，且催化活性无效。该蛋白质是分泌的，与微粒体甘油三酯转移蛋白一起作用，调节HNF4alpha诱导的丙型肝炎病毒感染性。这个基因在各种肿瘤中的表达下调，提示它可能作为肿瘤进展的负调控因子发挥作用。这个基因的可变剪接导致多个转录变异体。[RefSeq，2015年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PLA2G12B Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
