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中文人类
CUL3 - Cullin 3
Alias:
CUL-3
PHA2E
NEDAUS
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这个基因编码一个cullin蛋白家族的成员。编码的蛋白质作为E3泛素连接酶复合物的核心成分和支架蛋白，在特定蛋白质底物的多泛素化和后续降解中扮演关键角色。包括编码蛋白质的复合物还可能参与晚内体成熟。这个基因的突变是2E型假性醛固酮减少症的原因。已经观察到这个基因的替代剪接转录变体编码多种异构体。[RefSeq,2012年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CUL3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
