人类

LZTS2 - Leucine Zipper Tumor Suppressor 2

Alias:
LAPSER1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质属于亮氨酸拉链肿瘤抑制蛋白家族,该家族成员在转录调控和细胞周期控制中发挥作用。这个家族成员可以抑制β-连环蛋白介导的转录激活,是Wnt信号通路的一个负调控因子。它负调控中心体微管切点,对中央纺锤形成和胞质分裂完成是必要的。它与癌症有关,可能抑制细胞增殖并降低肿瘤发展的敏感性。这个基因的可变剪接导致多个转录变异体。[RefSeq,2015年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
14
5
11246 bp
72.76
43
--
3
12

LZTS2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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