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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
NCK2 - NCK Adaptor Protein 2
Alias:
GRB4
NCKbeta
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个NCK家族适配器蛋白质的成员。这个蛋白质包含三个SH3结构域和一个SH2结构域。这个蛋白质没有已知的催化功能,但已显示可以结合并招募涉及受体蛋白酪氨酸激酶调控的各种蛋白质。正是通过这些调控作用,这个蛋白质被认为参与细胞骨架的重组织。交替的转录剪接变异体,编码不同的异构体,已经被表征。[由RefSeq,2008年7月提供]
Related ID:
NCBI:8440
ENSEMBL:ENSG00000071051
HGNC:7665
UNIPROT:O43639
OMIM:604930
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8440
14
5
149820 bp
42.91
6
--
5
17
NCK2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
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Score
Mutations
No data available
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Interactions
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Name
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Status
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References Literature
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