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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ING5 - Inhibitor Of Growth Family Member 5
Alias:
p28ING5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种肿瘤抑制蛋白,可以抑制细胞生长并诱导细胞凋亡。这种蛋白包含一个PHD型锌指结构。它可以与肿瘤抑制因子p53和p300相互作用,p300是组蛋白乙酰转移酶复合物的组成部分,这表明它在转录调控中发挥作用。可变剪接和多个启动子和3'末端外显子的使用导致多个转录变异体。[RefSeq,2016年8月提供]
Related ID:
NCBI:84289
ENSEMBL:ENSG00000168395
HGNC:19421
UNIPROT:Q8WYH8
OMIM:608525
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
84289
11
8
42459 bp
27.75
9
--
4
18
ING5 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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