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中文人类
ANTXR1 - ANTXR Cell Adhesion Molecule 1
Alias:
ATR
GAPO
TEM8
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这个基因编码一种I型跨膜蛋白，是肿瘤特异性的内皮细胞标志物，与结直肠癌有关。已发现其编码的蛋白质也是炭疽杆菌毒素的接合蛋白或受体，炭疽病的病因是炭疽杆菌。三聚体炭疽毒素的保护抗原（PA）成分与这个受体蛋白质结合，将毒素成分传递到细胞质中。一旦进入细胞，炭疽毒素的其他两个成分水肿因子（EF）和致死因子（LF）就会破坏正常的细胞过程。已经描述了三种可变剪接的变异体，它们编码不同的蛋白质异构体。[RefSeq，2008年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ANTXR1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
