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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
BCAR3 - BCAR3 Adaptor Protein, NSP Family Member
Alias:
MIG7
NSP2
AND-34
SH2D3B
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
乳腺癌最初依赖于雌激素的生长和进展,并可以通过如他莫昔芬等抗雌激素药物抑制。然而,乳腺癌会发展成为抗雌激素抵抗。在寻找参与雌激素抵抗发展的基因时,发现了乳腺癌抗雌激素抵抗基因3。该基因编码细胞内信号转导的一个组成部分,导致人乳腺癌细胞的雌激素独立增殖。该蛋白质包含一个可能的src同源2(SH2)域,这是细胞酪氨酸激酶信号分子的标志,部分与细胞分裂周期蛋白CDC48同源。对于这个基因,已经发现了多种转录变体,编码不同的等位基因。[由RefSeq提供,2012年5月]
Related ID:
NCBI:8412
ENSEMBL:ENSG00000137936
HGNC:973
UNIPROT:O75815
OMIM:604704
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8412
33
12
286411 bp
92.57
51
--
5
21
BCAR3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
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Interactions
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Acting
Regulation
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Residues
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
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References Literature
Title
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IF
No Data Found!
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