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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Gsk3b - glycogen synthase kinase 3 beta
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括ATP结合活性;蛋白激酶活性;和信号受体结合活性。参与多种过程,包括神经元突起发育的调节;突触组织的调节;和对肽的反应。位于几种细胞组件中,包括树突棘;膜筏;和微管。是β-联蛋白降解复合体的一部分。在Schaffer collateral - CA1突触和谷氨酸能突触中活性。用于研究几种疾病,包括大脑中动脉梗死;心肌梗死;神经退行性疾病(多种);坐骨神经病;和血管性痴呆。几种疾病的生物标志物,包括动脉疾病(多种);糖尿病性脑病;精神抑郁症;癫痫状态;和2型糖尿病。该基因的人类同源物与阿尔茨海默病;肌萎缩侧索硬化;双相障碍;和精神分裂症有关。与人GSK3B(糖原合成酶激酶3β)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:84027
ENSEMBL:ENSRNOG00000002833
UNIPROT:P18266
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
84027
6
11
149669 bp
46.74
12
10
Gsk3b Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
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