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中文人类
CASP7 - Caspase 7
Alias:
MCH3
CMH-1
LICE2
CASP-7
ICE-LAP3
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这个基因编码半胱氨酸-天冬氨酸蛋白酶(caspase)家族的成员。caspases的序列激活在细胞凋亡的执行阶段起着核心作用。caspases作为无活性的前酶存在，在保守的天冬氨酸残基处经过蛋白水解加工产生两个亚基，大亚基和小亚基，它们二聚形成活性酶。编码的蛋白质的前体被caspase 3和10切割，在细胞死亡刺激后激活，并诱导凋亡。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[RefSeq提供，2012年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CASP7 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
