小鼠

Mmp1a - matrix metallopeptidase 1a (interstitial collagenase)

Alias:
Mcola
MMP-1a
Mcol-A
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码金属蛋白酶家族的一员,该家族参与组织重塑、伤口修复、动脉粥样硬化进展和肿瘤侵袭。编码的前原蛋白经历蛋白水解处理,生成成熟的、依赖锌的内肽酶,降解胶原蛋白。缺乏编码蛋白的小鼠对化学致癌剂诱导的肺癌发展和血管生成的敏感性降低。这个基因位于染色体9上其他金属蛋白酶基因簇中。[RefSeq,2016年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
10
12730 bp
53.49
4
3

Mmp1a Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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