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中文人类
PLA2G10 - Phospholipase A2 Group X
Alias:
SPLA2
GXPLA2
GXSPLA2
sPLA2-X
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这个基因编码磷酸脂酶A2家族的一员。可变剪接产生多种转录子变异体，其中至少一个编码前原蛋白，该前原蛋白在蛋白水解过程中被加工成成熟的酶。这个钙依赖的酶水解甘油磷酸脂产生游离脂肪酸和溶血磷脂。在一个例子中，这个酶催化花生四烯酸从细胞膜磷脂中释放，从而在产生各种炎症脂质介质，如前列腺素的过程中发挥作用。编码的蛋白质可能通过其在脂质代谢中的作用促进乳腺癌细胞的生存。[由RefSeq，2015年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PLA2G10 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
