人类

EIF2A - Eukaryotic Translation Initiation Factor 2A

Alias:
CDA02
EIF-2A
MST089
MSTP004
MSTP089
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个催化形成纯阿霉素敏感型80S起始复合物以及在低镁浓度下聚苯丙氨酸合成的真核翻译起始因子。这个基因不应与eIF2-alpha (EIF2S1, Gene ID: 1965),即eIF2翻译起始复合物的alpha亚基混淆。尽管这两个蛋白都在将启动子tRNA结合到40S核糖体亚基中发挥作用,但编码的蛋白是以依赖密码子的方式进行,而eIF2复合物需要ATP。这个基因的可变剪接导致多个转录变异体,它们编码不同的异构体。[RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
14
39230 bp
64.99
21
--
5
14

EIF2A Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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