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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
EIF2A - Eukaryotic Translation Initiation Factor 2A
Alias:
CDA02
EIF-2A
MST089
MSTP004
MSTP089
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个催化形成纯阿霉素敏感型80S起始复合物以及在低镁浓度下聚苯丙氨酸合成的真核翻译起始因子。这个基因不应与eIF2-alpha (EIF2S1, Gene ID: 1965),即eIF2翻译起始复合物的alpha亚基混淆。尽管这两个蛋白都在将启动子tRNA结合到40S核糖体亚基中发挥作用,但编码的蛋白是以依赖密码子的方式进行,而eIF2复合物需要ATP。这个基因的可变剪接导致多个转录变异体,它们编码不同的异构体。[RefSeq,2016年1月提供]
Related ID:
NCBI:83939
ENSEMBL:ENSG00000144895
HGNC:3254
UNIPROT:Q9BY44
OMIM:609234
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
83939
8
14
39230 bp
64.99
21
--
5
14
EIF2A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Alphabetical
Cell-specific RNA expression
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Name
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Status
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Link
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References Literature
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IF
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