Src - SRC proto-oncogene, non-receptor tyrosine kinase

Enables several functions, including estrogen receptor binding activity; insulin receptor binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular response to lipid; positive regulation of phosphorylation; and regulation of signal transduction. Located in caveola; neuron projection; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic specialization, intracellular component. Used to study Parkinsonism; brain ischemia; hypertension; status epilepticus; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in colorectal cancer (multiple); ductal carcinoma in situ; prostate cancer; thrombocytopenia; and type 2 diabetes mellitus. Orthologous to human SRC (SRC proto-oncogene, non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]