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中文人类
CASP3 - Caspase 3
Alias:
CPP32
SCA-1
CPP32B
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这个基因编码的蛋白质是一种半胱氨酸-天冬氨酸蛋白酶，在细胞凋亡的执行阶段发挥核心作用。编码的蛋白质切割并失活多(ADP-核糖)聚合酶，同时切割并激活固醇调节元件结合蛋白以及caspases 6, 7和9。这种蛋白质本身被caspases 8, 9和10加工。它是切割淀粉样蛋白-beta 4A前体蛋白的主要半胱天冬酶，这与阿尔茨海默病的神经元死亡有关。[由RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CASP3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
