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中文人类
BCL2L12 - BCL2 Like 12
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这个基因编码一个含有Bcl-2同源结构域2(BH2)的蛋白质家族成员。编码的蛋白质是一种抗凋亡因子，在细胞质中作为caspases 3和7的抑制剂发挥作用。在细胞核中，它与p53肿瘤抑制蛋白结合，防止其与目标基因结合。这个基因的过度表达在许多不同类型的癌症中都有检测到。在染色体3上有一个这个基因的假基因。可选的剪接导致多个转录变异体。[由RefSeq，2013年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BCL2L12 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
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Name
MGI
Strain of Origin
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Mutations
Related Drugs
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CAS Number
Status
Phase
Link
References Literature
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Year
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