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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Cdkn1b - cyclin-dependent kinase inhibitor 1B
Alias:
p27
Kip1
CDKN4
Cdki1b
P27KIP1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有Hsp70蛋白结合活性和分子伴侣结合活性。参与几个过程,包括调节细胞周期蛋白依赖性蛋白丝氨酸/苏氨酸激酶活性;对雌二醇的反应;和对葡萄糖的反应。位于细胞质和核中。是含蛋白质复合物的一部分。用于研究白内障;内分泌器官良性肿瘤(多种);不孕;多发性内分泌肿瘤;和心肌梗死。几种疾病的生物标志物,包括急性肾衰竭;肾小球肾炎(多种);肥胖症;肺动脉高压;和坐骨神经病。该基因的人类同源物与急性粒细胞白血病;乳腺癌;多发性内分泌肿瘤4型;和骨髓增生异常综合症有关。与人类CDKN1B(细胞周期蛋白依赖性激酶抑制剂1B)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:83571
ENSEMBL:ENSRNOG00000007249
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
83571
2
4
5111 bp
Unknown
20
4
Cdkn1b Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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