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Cdkn1b - cyclin-dependent kinase inhibitor 1B

Alias:
p27
Kip1
CDKN4
Cdki1b
P27KIP1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有Hsp70蛋白结合活性和分子伴侣结合活性。参与几个过程,包括调节细胞周期蛋白依赖性蛋白丝氨酸/苏氨酸激酶活性;对雌二醇的反应;和对葡萄糖的反应。位于细胞质和核中。是含蛋白质复合物的一部分。用于研究白内障;内分泌器官良性肿瘤(多种);不孕;多发性内分泌肿瘤;和心肌梗死。几种疾病的生物标志物,包括急性肾衰竭;肾小球肾炎(多种);肥胖症;肺动脉高压;和坐骨神经病。该基因的人类同源物与急性粒细胞白血病;乳腺癌;多发性内分泌肿瘤4型;和骨髓增生异常综合症有关。与人类CDKN1B(细胞周期蛋白依赖性激酶抑制剂1B)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
4
5111 bp
Unknown
20
4

Cdkn1b Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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