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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Abcb11 - ATP binding cassette subfamily B member 11
Alias:
Bsep
Spgp
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
ABC-类型的外源性物质转运体活性;胆汁酸膜转运体活性;以及碳水化合物膜转运体活性。参与几个过程,包括通道型胆汁酸转运;对17α-乙炔基雌二醇的反应;以及外源性物质膜转运。位于高尔基体膜;细胞内小管;以及回收内质网膜。用于研究胆汁淤积。酒精性肝炎和胆汁淤积的标志物。这个基因的人类同源物与良性复发性肝内胆汁郁2;肝内胆汁郁;肝硬化;以及进行性家族性肝内胆汁郁2有关。与人类ABCB11(ATP结合盒亚家族B成员11)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:83569
ENSEMBL:ENSRNOG00000050860
UNIPROT:O70127
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
83569
4
29
95944 bp
146.26
6
14
Abcb11 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Name
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