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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Timeless - timeless circadian regulator
Alias:
Tim
rTIM
rTLP
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质具有高度保守性,参与损伤或应激后的细胞生存、DNA聚合酶ε活性的增加、端粒长度的维持以及上皮细胞形态发生。编码的蛋白质还在昼夜节律自调循环中发挥作用,与周期基因(Per1、Per2和Per3)以及其他基因相互作用,以降低Clock/Arntl对Per1的激活。这个基因或其表达的改变可能促进前列腺癌、肺癌、乳腺癌和精神障碍的发生。[RefSeq,2014年2月提供]
Related ID:
NCBI:83508
ENSEMBL:ENSRNOG00000031916
UNIPROT:Q9Z2Y1
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
83508
8
29
23966 bp
138.56
7
4
Timeless Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Acting
Regulation
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Type
Name
MGI
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