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中文人类
CASP2 - Caspase 2
Alias:
ICH1
NEDD2
CASP-2
NEDD-2
PPP1R57
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这个基因编码半胱氨酸-天冬氨酸蛋白酶(caspase)家族的成员。caspases通过特定蛋白质底物的蛋白水解切割来调节细胞凋亡。编码的蛋白质可能在应激诱导的细胞死亡通路、细胞周期维持和肿瘤发生的抑制中发挥作用。这个基因的过度表达可能在神经退行性疾病中发挥作用，包括阿尔茨海默病、亨廷顿病和颞叶癫痫。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[由RefSeq，2011年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CASP2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
