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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
H2BC21 - H2B Clustered Histone 21
Alias:
H2B
H2BE
H2BQ
GL105
H2B.1
H2BFQ
H2BGL105
H2B-GL105
HIST2H2BE
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
组蛋白是负责真核生物染色体纤维核小体结构的基本核蛋白质。四种核心组蛋白(H2A、H2B、H3和H4)中的每一种都有两个分子,形成一个八聚体,大约146个碱基对的DNA围绕这个八聚体被包装在重复的单元中,称为核小体。连接蛋白H1与核小体之间的连接DNA相互作用,并将染色质压缩成更高阶的结构。这个基因编码一个依赖于复制的组蛋白,是组蛋白H2B家族的成员,通过使用保守的茎环终止基序和polyA添加基序产生两个转录本。该蛋白质具有抗菌和抗真菌的抗菌活性。[由RefSeq,2015年8月提供]
Related ID:
NCBI:8349
ENSEMBL:ENSG00000184678
HGNC:4760
UNIPROT:Q16778
OMIM:601831
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Reference
8349
1
1
2224 bp
13.92
2
--
--
27
H2BC21 Genetics information (-)
GRCh38
Sequence Homology
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* This data comes from NCBI.
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