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Glis2 - GLIS family zinc finger 2

Alias:
Nkl
Gli5
Klf16
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性结合RNA聚合酶II,并调节RNA聚合酶II转录调控区的DNA结合活性。参与平滑肌抑制信号通路负调控和转录调控,DNA模板。在多个过程的上游或内部发挥作用,包括造血干细胞稳态、蛋白质定位至细胞核的正调控以及RNA聚合酶II的转录调控。位于细胞质、非运动性纤毛和核斑点中。在多个结构中表达,包括早期概念体、肠道、神经系统、卵母细胞和视网膜层。用于研究肾囊性纤维化7。该基因的人类同源物与肾囊性纤维化7有关。与人类的GLIS2(GLIS家族锌指2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
9
7
30860 bp
55.84
5
7

Glis2 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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