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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Tfap4 - transcription factor AP4
Alias:
AP-4
Tcfap4
bHLHc41
D930048N17Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;E-box结合活性;以及组蛋白脱乙酰酶结合活性。参与细胞对地塞米松刺激的应答;大分子代谢过程的负调控;以及蛋白质复合物的组装。在涉及凋亡信号通路和RNA聚合酶II正向调控转录的上游或正调控半胱氨酸型内肽酶活性中发挥作用。位于细胞核中。是转录抑制复合物的一部分。在包括中枢神经系统;背根神经节;早期概念期;生殖泌尿系统;和肠道在内的几个结构中表达。与人类的TFAP4(转录因子AP-4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:83383
ENSEMBL:ENSMUSG00000005718
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
83383
16
7
16101 bp
Unknown
7
11
Tfap4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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