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中文人类
H2AC4 - H2A Clustered Histone 4
Alias:
H2A/m
H2AC8
H2AFM
HIST1H2AB
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组蛋白是负责真核生物染色体纤维核小体结构的基本核蛋白质。该结构由约146bp的DNA围绕一个核小体、一个由四个核心组蛋白(H2A、H2B、H3和H4)每对组成的八聚体组成。通过连接蛋白组蛋白H1与核小间DNA的相互作用，染色质纤维进一步压缩，形成更高阶的染色质结构。该基因无内含子，编码一个依赖于复制的组蛋白，属于组蛋白H2A家族。该基因的转录本缺乏polyA尾；相反，它们含有一个回文终止元件。该基因位于染色体6p22-p21.3上的大型组蛋白基因簇中。[RefSeq，2015年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
H2AC4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
