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中文人类
TRRAP - Transformation/transcription Domain Associated Protein
Alias:
Tra1
TR-AP
DEDDFA
DFNA75
PAF400
STAF40
PAF350/400
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这个基因编码一个与磷酸肌醇3-激酶相关激酶(PIKK)家族相关的庞大多结构域蛋白质。编码的蛋白质是许多组蛋白乙酰转移酶(HAT)复合物的常见组成部分，并通过将HAT复合物招募到染色质上，在转录和DNA修复中发挥作用。这个基因的调控异常可能在几种癌症中发挥作用，包括多形性胶质母细胞瘤。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[RefSeq,2011年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TRRAP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
