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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CAPN2 - Calpain 2
Alias:
CANP2
mCANP
CANPL2
CANPml
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
钙激活中性蛋白酶(calpains)是一种非溶酶体的细胞内半胱氨酸蛋白酶,受钙离子调节。哺乳动物的calpains包括泛素存在的、胃特异性的和肌肉特异性的蛋白质。泛素存在的酶由具有不同大型催化亚基的异源二聚体组成,这些亚基与一个公共的小型调节亚基相关联。这个基因编码泛素存在酶的大型亚基,即calpain 2。在5'UTR中已经报道了多个不同的转录起始位点。已经发现这个基因有两个编码不同异构体的转录变异体。[RefSeq,2009年3月提供]
Related ID:
NCBI:824
ENSEMBL:ENSG00000162909
HGNC:1479
UNIPROT:P17655
OMIM:114230
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
824
3
21
74422 bp
80.00
47
--
4
12
CAPN2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Name
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CAS Number
Status
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Link
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References Literature
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