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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CAPN1 - Calpain 1
Alias:
CANP
muCL
CANP1
SPG76
CANPL1
muCANP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
钙激活中性蛋白酶(calpains)是一种非溶酶体的细胞内半胱氨酸蛋白酶,主要由钙离子激活。哺乳动物的calpains包括泛素存在的、胃特异性的和肌肉特异性的蛋白质。泛素存在的酶由具有不同大催化亚基的异源二聚体组成,并与一个公共的小调节亚基关联。这个基因编码泛素存在酶的催化亚基,即钙激活中性蛋白酶1。已经发现这个基因有几个转录变异体,编码两种不同的异构体。[RefSeq,2010年11月提供]
Related ID:
NCBI:823
ENSEMBL:ENSG00000014216
HGNC:1476
UNIPROT:P07384
OMIM:114220
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
823
5
22
30634 bp
81.89
236
1
5
17
CAPN1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
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Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Type
Name
MGI
Strain of Origin
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Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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