Enables sterol 12-alpha-hydroxylase activity. Involved in bile acid signaling pathway; response to cholesterol; and response to nutrient levels. Predicted to be located in endoplasmic reticulum membrane. Biomarker of extrahepatic cholestasis; non-alcoholic fatty liver disease; and premature menopause. Orthologous to human CYP8B1 (cytochrome P450 family 8 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]