人类

SPACA1 - Sperm Acrosome Associated 1

Alias:
SAMP32
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
抗精子抗体与不明原因不育病例的相关性暗示了这些抗体在阻止受精中的作用。免疫不育的诊断和治疗的改进,以及针对避孕的蛋白质的鉴定,都依赖于相关精子抗原的鉴定和特征描述。这个基因编码的蛋白质被来自不育男性的抗精子抗体识别。此外,针对该重组蛋白质产生的抗体阻止了体外受精。该蛋白质定位在精子的顶体膜和成熟的精子中,被认为在顶体形态发生和精子-卵子结合和融合中分别发挥作用。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
7
19938 bp
32.14
16
1
2
3

SPACA1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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