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中文人类
ADAMTS10 - ADAM Metallopeptidase With Thrombospondin Type 1 Motif 10
Alias:
WMS
WMS1
ADAM-TS10
ADAMTS-10
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这个基因属于锌依赖的ADAMTS（整合素和金属蛋白酶结构域具有血栓素类型-1基序）家族蛋白酶。ADAMTS蛋白酶是复杂的分泌酶，包含一个reprolysin类型的prometalloprotease结构域，连接到一个具有高度保守结构的辅助结构域，该结构域至少包含一个血栓素类型1重复序列。已经证明它们在结缔组织组织、凝血、炎症、关节炎、血管生成和细胞迁移中具有重要作用。这个基因的产物在生长和皮肤、晶状体和心脏发育中起主要作用。它也是常染色体隐性Weill-Marchesani综合征的候选基因。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ADAMTS10 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
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Residues
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Score
Related Mouse Models
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Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
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PMID
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Year
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