人类

TLR10 - Toll Like Receptor 10

Alias:
CD290
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Toll样受体(TLR)家族的一员,在病原体识别和先天免疫激活中起基本作用。TLRs从果蝇到人类高度保守,并在结构和功能上相似。它们识别感染剂上表达的病原体相关分子模式(PAMPs),并调节产生有效免疫发展所需的细胞因子。各种TLR以不同的表达模式表达。这个基因在淋巴组织中表达最高,如脾脏、淋巴结、胸腺和扁桃体。已经发现这个基因的多个可变剪接转录变异体,它们编码不同的蛋白质异构体。[RefSeq,2010年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
11
4
10753 bp
94.56
37
--
--
7

TLR10 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
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