Rock1 - Rho-associated coiled-coil containing protein kinase 1

Enables small GTPase binding activity. Involved in cytoskeleton organization; positive regulation of gene expression; and response to transforming growth factor beta. Acts upstream of or within Rho protein signal transduction. Predicted to be located in lamellipodium; plasma membrane; and ruffle. Predicted to be part of amyloid-beta complex. Predicted to be active in cytoplasmic stress granule and cytoskeleton. Orthologous to human ROCK1 (Rho associated coiled-coil containing protein kinase 1). [provided by Alliance of Genome Resources, Apr 2022]