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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Nfkb1 - nuclear factor kappa B subunit 1
Alias:
EBP-1
NF-kB
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有热激蛋白结合活性;具有相同的蛋白质结合活性;并具有转录顺式调控区域结合活性。参与几个过程,包括细胞对细胞因子刺激的响应;细胞对脂质响应;以及基因表达调控。在细胞对细胞因子刺激的响应和细胞对有机环状化合物的响应的上游或内部发挥作用。位于细胞质;神经元突起;和细胞核中。蛋白质含有复合物的一部分。用于研究脂肪肝疾病。是酒精性肝炎、非酒精性脂肪性肝炎和短暂性脑缺血的生物标志物。该基因的人类同源物涉及几种疾病,包括癌(多种);常见可变免疫缺陷;黑素瘤;前列腺癌;和热带痉挛性下肢瘫痪。与人类NFKB1(核因子kappa B亚基1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:81736
ENSEMBL:ENSRNOG00000023258
UNIPROT:Q63369
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
81736
5
25
115922 bp
Unknown
16
--
Nfkb1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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