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中文人类
TXNDC5 - Thioredoxin Domain Containing 5
Alias:
HCC2
ERP46
HCC-2
STRF8
PDIA15
UNQ364
ENDOPDI
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这个基因编码一种二硫化物异构酶(PDI)家族的成员，该家族是内质网(ER)蛋白，负责催化蛋白质折叠和巯基-二硫化物交换反应。编码的蛋白质具有N端内质网(ER)信号序列，三个催化活性硫氧还蛋白结构域和一个C端ER保留序列。其表达受到缺氧诱导，其作用可能是保护缺氧细胞免受凋亡。可变剪接产生多种转录变异体。还存在这个基因与相邻的上游BLOC1S5基因之间的读穿转录。[RefSeq提供，2016年12月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TXNDC5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
