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中文人类
CAMK2A - Calcium/calmodulin Dependent Protein Kinase II Alpha
Alias:
CAMKA
MRD53
MRT63
CaMKIIalpha
CaMKIINalpha
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这个基因的产物属于丝氨酸/苏氨酸蛋白激酶家族，以及Ca(2+)/钙调蛋白依赖性蛋白激酶亚家族。钙信号对于谷氨酸能突触的可塑性几个方面至关重要。这个钙钙调蛋白依赖性蛋白激酶由四个不同的链组成：α链，β链，γ链和δ链。这个基因编码的α链对于海马长时程增强（LTP）和空间学习是必需的。除了其钙-钙调蛋白（CaM）依赖性活性外，这个蛋白还可以经历自磷酸化，导致CaM非依赖性活性。已经在这个基因中鉴定出几种编码不同异型的转录变异体。[由RefSeq，2018年6月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CAMK2A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
