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中文人类
TCL1A - TCL1 Family AKT Coactivator A
Alias:
TCL1
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TCL1基因在人类中的过度表达与成熟T细胞白血病的发展有关，其中染色体重排使TCL1基因与T细胞抗原受体（TCR）-alpha（MIM 186880）或TCR-beta（MIM 186930）调节元件紧密接近（Virgilio等人，1998年总结[PubMed 9520462]）。在正常T细胞中，TCL1表达于CD4-/CD8-细胞中，而在分化较晚阶段的细胞中不表达。TCL1作为细胞生存激酶AKT（MIM 164730）的协同激活因子发挥作用（Laine等人，2000年[PubMed 10983986]）。[由OMIM于2010年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TCL1A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
Alphabetical
Interactions
Acting
Regulation
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Score
Related Mouse Models
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Name
MGI
Strain of Origin
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Mutations
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References Literature
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